学习经历

1985/09-1989/07  华中农业大学，生命科学与技术学院微生物专业，学士
1989/09-1992/07  华中农业大学，生命科学与技术学院微生物专业，硕士
1995/09-1998/07  武汉大学，生命科学学院遗传专业，博士

主要工作经历与任职情况

1992/07-1994/07　　武汉大学生命科学学院，助教

1998/11-2001/09　　美国内布拉斯加林肯大学，博士后

1994/07-2001/11　　武汉大学生命科学学院，讲师

2001/11-2005/11　　武汉大学生命科学学院，副教授

2006/03-2006/12　　美国爱尔瓦州立大学，合作进修研究

2005/11-至今　　　   武汉大学生命科学学院，教授

主要社会兼职

2015/12-至今   湖北省遗传学会理事

主要科研奖励和个人荣誉职

2002年，湖北省杰出青年基金获得者

2005年，教育部科学技术奖（自然科学奖）二等奖（排名第2）

2007年，教育部新世纪人才

承担课程

本科生：基因工程

研究生：植物分子细胞遗传学

主持课程项目

先后主持8项国家自然科学基金课题，1项转基因专项，1项国家支撑计划子课题，1项教育部留学生回国基金，2项湖北省自然科学基金，1项省重点基金以及湖北省首出青年基金和教育部新世纪人才项目。

最近发表的论文（#并列第一作者，*通讯作者）：

1) Jiaqi Hou, Xueke Zheng, Ruifei Ren, Qipeng Shi, Huangzhuo Xiao, Zhenfei Chen, Mengxia Yue, Yequn Wu, Haoli Hou, Lijia Li*. (2022) The histone deacetylase 1/GSK3/SHAGGY-like kinase 2/BRASSINAZOLE-RESISTANT 1 module controls lateral root formation in rice. Plant Physiology, 189: 858–873.

2) Hong Zhou#, Yapei Wang#, Qing Wang, Le Li, Yan Hu, Yequn Wu, Mayank Gautam, Lijia Li*. (2021) R-loops mediate transcription-associated formation of human rDNA secondary constrictions. Journal of cellular biochemistry, 22 (10): 1517-1533.

3) Mengxia Yue, Mayank Gautam, Zhenfei Chen, Jiaqi Hou, Xueke Zheng, Haoli Hou, Lijia Li*. (2021) Histone acetylation of 45S rDNA correlates with disrupted nucleolar organization during heat stress response in Zea mays L.. Physiologia plantarum, 172 (4): 2079-2089.

4) Jiaqi Hou, Ruifei Ren, Huangzhuo Xiao, Zhenfei Chen, Jinfu Yu, Haorui Zhang, Qipeng Shi, Haoli Hou, Shibin He*, Lijia Li*. (2021) Characteristic and evolution of HAT and HDAC genes in Gramineae genomes and their expression analysis under diverse stress in Oryza sativa. Planta, 253(3):72.

5) Hong Zhou#, Le Li#, Qing Wang#, Yan Hu, Weiwei Zhao, Mayank Gautam, Lijia Li*. (2020) H3K9 demethylation-induced R-Loop accumulation is linked to disorganized nucleoli. Frontiers in Genetics, 11:43.

6) Hao Zhang, Mengxia Yue，Xueke Zheng，Mayank Gautam，Shibin He, Lijia Li*. (2018) The role of promoter-associated histone acetylation of haem oxygenase-1 (HO-1) and giberellic acid-stimulated like-1 (GSL-1) genes in heat-induced lateral root primordium inhibition in maize. Frontiers in Plant Science, 9: 1520.

7) Haoli Hou, Xueke Zheng, Hao Zhang, Mengxia Yue, Yan Hu, Hong Zhou, Qing Wang, Chengshen Xie, Pu Wang, and Lijia Li*. (2017) Histone deacetylase is required for GA-induced programmed cell death in maize aleurone layers. Plant Physiology, 175(3): 1484-1496.

8) Xueke Zheng, Haoli Hou, Hao Zhang, Mengxia Yue, Yan Hu, Lijia Li*. (2017) Histone acetylation is involved in GA-mediated 45S rDNA decondensation in maize aleurone layers. Plant Cell Report, 31(1): 115-123.

9) Qing Wang, Pu Wang, Hong Zhou, Yan Hu, Chengshen Xie, Fei Gao, Ningjie Ma, Haoli Hou, Hao Zhang, Lijia Li*. (2017) 5-Azacytidine specifically inhibits the NIH-3T3 PCD process induced by TNF-alpha and cycloheximide via affecting BCL-XL. Journal of Cellular Biochemistry, 119(2):1501-1510.

10) Fei Gao, Ningjie Ma, Hong Zhou, Qing Wang, Hao Zhang, Pu Wang, Haoli Hou, Huan Wen, Lijia Li*. (2016) Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes. International Journal of Nanomedicine, 11: 3859–3874.

11) Pu Wang, Hao Zhang, Haoli Hou, Qing Wang, Yingnan Li, Yan Huang, Liangfu Xie, Fei Gao, Shibin He, Lijia Li*. (2016) Cell cycle arrest induced by inhibitors of epigenetic modifications in maize (Zea mays) seedling leaves: characterization of the process and possible mechanisms involved. New Phytologist, 221(2): 646–657.

12) Haoli Hou, Pu Wang, Hao Zhang, Huan Wen, Fei Gao, Ningjie Ma, Qing Wang, Lijia Li*. (2015) Histone acetylation is involved in gibberellin-regulated sodCp gene expression in maize aleurone layers. Plant and Cell Physiology, 56(11): 2139-2149.

13) Pu Wang, Lin Zhao, Haoli Hou, Hao Zhang, Yan Huang, Yapei Wang, Hui Li, Fei Gao, Shihan Yan, Lijia Li*. (2015) Epigenetic changes are associated with programmed cell death induced by heat stress in seedling leaves of Zea mays. Plant and Cell Physiology, 56(5): 965-976.

14) Shibin He#, Xu Yu#, Xiangwu Wang, Junjun Tan, Shihan Yan, Pu Wang, Bi-Hai Huang, Zhi-Ling Zhang*, Lijia Li*. (2014) Fast magnetic isolation of simple sequence repeat markers in microfluidic channels. Lab on a Chip, 14: 1410-1414.

15) Shihan Yan, Lin Zhao, Hui Li, Qi Zhang, Junjun Tan, Min Huang, Shibin He, Lijia Li*. (2013) Single-walled carbon nanotubes selectively influence maize root tissue development accompanied by the change in the related gene expression. Journal of Hazardous Materials, 246– 247: 110– 118.

16) Shibin He#，Bi-Hai Huang#，Junjun Tan，Qing-Ying Luo，Yi Lin，Jun Li，Yong Hu，Lu Zhang，Shihan Yan，Qi Zhang，Dai-Wen Pang*，Lijia Li*. (2011) One-to-one quantum dot-labeled single long DNA probes. Biomaterials, 32(23): 5471-5477.

出版教材

李立家，肖庚富，杨飞，朱爱华。（2018）《基因工程》，第二版普通高等教育“十三五”规划教材，科学出版社。