姚辰为我院2006级校友，人在美国，她想招博士后
得克萨斯大学西南医学中心免疫系姚辰实验室招聘博后
实验室介绍
美国德克萨斯大学西南医学中心(UTSW)是世界知名的医学研究中心之一。西南医学中心致力于多学科交叉研究和培养基础和临床科研人员。该中心共产生了6名诺贝尔奖获得者，25名美国国家科学院院士，17名美国国家医学院院士，及14名HHMI。姚辰课题组隶属于免疫系和肾癌研究中心。用老鼠模型，病人样品，和包括单细胞测序在内的先进技术，该课题组致力于研究慢性感染和癌症中T细胞分化和功能的分子和细胞机制，进而提高疫苗和免疫疗法的效率。
职位简介
需聘任高水平博后2名。博后的培养项目及待遇的详细信息可从如下网站得知https://www.utsouthwestern.edu/education/graduate-school/postdoctoral-scholars/。博后工资根据NIH标准每年$55,000-$65,000。导师会帮助博后申请独立所需基金。博后可以做自己主导的课题的co-responding authors。
应聘条件
申请人需已获得或即将获得生物学方面的博士学位，包括免疫，微生物，癌症或其他相关领域的博士学位。可以处理小鼠及病人样品。有处理肿瘤模型经验者优先。有处理高通量测序经验者优先。
实验室网页
https://www.utsouthwestern.edu/labs/yao/
About the PI and the lab
A postdoctoral fellow position is open in the laboratory of Dr. Chen Yao in the Department of Immunology and the Kidney Cancer Program at the UT Southwestern Medical Center. The long-term goal of Yao laboratory is to identify molecular and cellular targets that can be harnessed to enhance the efficacy of vaccines and immunotherapies against infectious diseases and cancer. The Yao lab utilizes systems immunology approaches to identify key regulators of T-cell differentiation and function. Ongoing projects in the laboratory include: 1) Identify novel molecular regulators of long-term antitumor T cell immunity; 2) Identify biomarkers predicting the clinical outcome of cancer immunotherapy; 3) Dissect the mechanisms involved in the T cell response to chronic viral infections.
Dr. Yao received her PhD degree fromthe University of Minnesota under the supervision of Daniel Kaplan. She completed her postdoctoral training in the laboratory led by John O’Shea at the National Institutes of Health. Dr. Yao is currently an assistant professor in the Department of Immunology and the Kidney Cancer Program at UT Southwestern Medical Center. Dr. Yao is an awardee of the NIAID New Innovators Awards (DP2) and the CPRIT First-Time, Tenure-Track Faculty Scholar Award.
Relevant publications:
1. Yao C*, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, Moseman EA, Cheng J, D’Antonio MA, Shi W, Shi J, Kometani K, Kurosaki T, Wherry EJ, Afzali B, Gattinoni L, Zhu Y, McGavern DB, O’Shea JJ, Schwartzberg PL,Wu T*.(2021)BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8 T cells.Nature Immunology,(online). DOI:10.1038/s41590-021-00868-7 *corresponding authors.
2. Yao C, Sun HW, Lacey NE, Ji Y, Moseman EA, Shih HY, Heuston EF, Kirby M, Anderson S, Chen J, Khan O, Handon R, Reilley J, Fioravanti J, Hu J, Gossa S, Wherry EJ, Gattinoni L, McGavern DB, O'Shea JJ*, Schwartzberg PL*,Wu T*.Single-Cell RNA-Seq Reveals TOX as a Key Regulator of CD8+ T cell Persistence in Chronic Infection.Nature Immunology, 2019 Jul;20(7):890-901. PMID: 31209400
Requirement:
· PhD degree in immunology, microbiology, cancer biology or relevant fields.
· Comfortable working with mice and/or patient samples
· Experience with mouse cancer model is preferred
· Experience with bioinformatics and next-generation sequencing is preferred but not required
Candidates who meet the above criteria are welcome to send their CV, cover letter, and contact information of three referees to Dr. Chen Yao atChen.Yao@UTSouthwestern.edu
The Yao lab values trainee's professional development. The PI will assist trainees in applying for career development grants. In addition, the trainees can share co-responding authors for projects driven by themselves.
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